Haptoglobin anticorps (AA 70-286)

N° du produit ABIN1886626

Cet anticorps Lapin Polyclonal détecte spécifiquement Haptoglobin dans WB, IHC et IF. Il présente une réactivité envers Humain.

Aperçu rapide pour Haptoglobin anticorps (AA 70-286) (ABIN1886626)

Antigène: Haptoglobin (HP)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Haptoglobin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-Haptoglobin anticorps

Épitope: AA 70-286

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 70 and 286 of Human HP

Information d'application

Indications d'application: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.250
Immunofluorescence: 1.100-1.200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: Biohazard Informations: This product contains thimerosal which is hazardous.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Détails sur Haptoglobin

Antigène: Haptoglobin (HP)

Autre désignation: Haptoglobin

Sujet: This gene encodes a preproprotein, which is processed to yield both alpha and beta chains, which subsequently combine as a tetramer to produce haptoglobin.Haptoglobin functions to bind free plasma hemoglobin, which allows degradative enzymes to gain access to the hemoglobin, while at the same time preventing loss of iron through the kidneys and protecting the kidneys from damage by hemoglobin.Mutations in this gene and/or its regulatory regions cause ahaptoglobinemia or hypohaptoglobinemia.This gene has also been linked to diabetic nephropathy, the incidence of coronary artery disease in type 1 diabetes, Crohn's disease, inflammatory disease behavior, primary sclerosing cholangitis, susceptibility to idiopathic Parkinson's disease, and a reduced incidence of Plasmodium falciparum malaria.A similar duplicated gene is located next to this gene on chromosome 16.Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq]

Poids moléculaire: 38 kDa

ID gène: 3240

NCBI Accession: NM_001126102, NP_001119574

Pathways: Transition Metal Ion Homeostasis