SSRP1 anticorps (AA 75-308)

N° du produit ABIN1886647

Cet anticorps Lapin Polyclonal détecte spécifiquement SSRP1 dans WB et IHC. Il présente une réactivité envers Humain.

Aperçu rapide pour SSRP1 anticorps (AA 75-308) (ABIN1886647)

Antigène: SSRP1 (Structure Specific Recognition Protein 1 (SSRP1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SSRP1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-SSRP1 anticorps

Épitope: AA 75-308

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 75 and 308 of SSRP1

Information d'application

Indications d'application: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.250

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: Biohazard Informations: This product contains thimerosal which is hazardous.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Détails sur SSRP1

Antigène: SSRP1 (Structure Specific Recognition Protein 1 (SSRP1))

Autre désignation: SSRP1

Sujet: The protein encoded by this gene is a subunit of a heterodimer that, along with SUPT16H, forms chromatin transcriptional elongation factor FACT.FACT interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation.FACT and cisplatin-damaged DNA may be crucial to the anticancer mechanism of cisplatin.This encoded protein contains a high mobility group box which most likely constitutes the structure recognition element for cisplatin-modified DNA.This protein also functions as a co-activator of the transcriptional activator p63.An alternatively spliced transcript variant of this gene has been described, but its full-length nature is not known.[provided by RefSeq]

Poids moléculaire: 81 kDa

ID gène: 6749

NCBI Accession: NM_003146, NP_003137

Pathways: Chromatin Binding