IPO7 anticorps (AA 976-1038)

N° du produit ABIN1886728

Cet anticorps Lapin Polyclonal détecte spécifiquement IPO7 dans WB, IHC et IF. Il présente une réactivité envers Humain.

Aperçu rapide pour IPO7 anticorps (AA 976-1038) (ABIN1886728)

Antigène: IPO7 (Importin 7 (IPO7))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IPO7 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-IPO7 anticorps

Épitope: AA 976-1038

Purification: Purified by antigen-affinity chromatography.

Immunogène: Synthetic peptide contain a sequence corresponding to a region within amino acids 976 and 1038 of Importin-7

Information d'application

Indications d'application: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.250
Immunofluorescence: 1.100-1.200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 1 x PBS, 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: Biohazard Informations: This product contains thimerosal which is hazardous.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Détails sur IPO7

Antigène: IPO7 (Importin 7 (IPO7))

Autre désignation: Importin-7

Sujet: The importin-alpha/beta complex and the GTPase Ran mediate nuclear import of proteins with a classical nuclear localization signal.The protein encoded by this gene is a member of a class of approximately 20 potential Ran targets that share a sequence motif related to the Ran-binding site of importin-beta.Similar to importin-beta, this protein prevents the activation of Ran's GTPase by RanGAP1 and inhibits nucleotide exchange on RanGTP, and also binds directly to nuclear pore complexes where it competes for binding sites with importin-beta and transportin.This protein has a Ran-dependent transport cycle and it can cross the nuclear envelope rapidly and in both directions.At least four importin beta-like transport receptors, namely importin beta itself, transportin, RanBP5 and RanBP7, directly bind and import ribosomal proteins.[provided by RefSeq]

Poids moléculaire: 120 kDa

ID gène: 10527

NCBI Accession: NM_006391, NP_006382

Pathways: Protein targeting to Nucleus