Ki-67 anticorps (N-Term)

N° du produit ABIN1886792

L’anticorps Lapin Polyclonal anti-Ki-67 a été validé pour IHC, IF et ICC. Il convient pour détecter Ki-67 dans des échantillons de Humain.

Aperçu rapide pour Ki-67 anticorps (N-Term) (ABIN1886792)

Antigène: Ki-67 (MKI67) (Antigen Identified By Monoclonal Antibody Ki-67 (MKI67))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Ki-67 est non-conjugé

Application: Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Détail du produit anti-Ki-67 anticorps

Épitope: N-Term

Immunogène: KLH conjugated synthetic peptide derived from human Ki67 N-terminus

Information d'application

Indications d'application: Suggested dilutions:
Western blotting: 1.100-1.500
Immunohistochemistry 1.100-1.500

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 0.01 M PBS, pH 7.4 with 10 mg/ml BSA and 0.1 % Sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Stock: -20 °C

Stockage commentaire: Store at -20 °C/1 year

Date de péremption: 12 months

Détails sur Ki-67

Antigène: Ki-67 (MKI67) (Antigen Identified By Monoclonal Antibody Ki-67 (MKI67))

Autre désignation: Ki67

Sujet: Ki67 antigen is the prototypic cell cycle related nuclear protein, expressed by proliferating cells in all phases of the active cell cycle (G1, S, G2 and M phase).It is absent in resting (G0) cells.Ki67 antibodies are useful in establishing the cell growing fraction in neoplasms (immunohistochemically quantified by determining the number of Ki67 positive cells among the total number of resting cells = Ki67 index).In neoplastic tissues the prognostic value is comparable to the tritiated thymidine labelling index.The correlation between low Ki67 index and histologically low grade tumours is strong.Ki67 is routinely used as a neuronal marker of cell cycling and proliferation.Sueishi M.et al.J.Biol.Chem.275:28888-28892(2000) Takagi M.et al.J.Biol.Chem.276:25386-25391(2001) Beausoleil S.A.et al.Proc.Natl.Acad.Sci.U.S.A.101:12130-12135(2004) Olsen J.V.et al.Cell 127:635-648(2006)
Synonyms: KIA, Ki-67, Ki67, MKI67

Poids moléculaire: 358 kDa

UniProt: P46013

Pathways: Glycosaminoglycan Metabolic Process