Neurturin anticorps (AA 178-193)

N° du produit ABIN1886843

L’anticorps Lapin Polyclonal anti-Neurturin a été validé pour WB, ELISA et IHC. Il convient pour détecter Neurturin dans des échantillons de Humain.

Aperçu rapide pour Neurturin anticorps (AA 178-193) (ABIN1886843)

Antigène: Neurturin (NRTN)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Neurturin est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-Neurturin anticorps

Épitope: AA 178-193

Purification: Affinity chromatography purified via peptide column

Immunogène: Peptide corresponding to amino acids 178 to 193 of human neurturin.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Conseil sur la manipulation: Avoid freezing and thawing repeatly.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Détails sur Neurturin

Antigène: Neurturin (NRTN)

Autre désignation: Neurturin

Sujet: Glial cell line-derived neurotrophic factor (GDNF) plays key roles in the control of vertebrate neuron survival and differentiation.A novel neurotrophic factor was recently cloned from human and mouse and designated neurturin.Physiological responses to neurturin (NTN) require the presence of receptor tyrosine kinase RET and a novel glycosylphosphatidylinositol linked receptor NTNRalpha.The cDNAs encoding NTNRalpha from human, rat, chicken, and mouse have been cloned recently and termed GDNFRbeta, Ret ligand 2 (RETL2) or TGF-beta-related neurotrophic factor receptor 2 (TrnR2) and nominated as GFRalpha-2 recently.NTN binds to and forms a complex with GFRalpha-2 and the Ret PTK and activates the RET receptor tyrosine kinase pathway.Both NTN and GDNF can activate the MAP kinase and phosphatidylinositol 3-kinase pathways and play a critical role in the development of many neuronal populations.Neurturin and GDNF define a new family of neurotrophic factors.

Poids moléculaire: 14 kDa

NCBI Accession: NP_004549