STS anticorps (AA 182-195)

N° du produit ABIN1886844

Détail du produit anti-STS anticorps

Antigène: STS (Steroid Sulfatase (STS))

Épitope: AA 182-195

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp STS est non-conjugé

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Purification: Affinity chromatography purified via peptide column

Immunogène: Synthetic peptide corresponding to amino acids 182 to 195 of human ASC.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Conseil sur la manipulation: Avoid freezing and thawing repeatly.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Détails sur STS

Antigène: STS (Steroid Sulfatase (STS))

Autre désignation: ASC (STS Produits)

Synonymes: anticorps 9130417A21Rik, anticorps Asc, anticorps CARD5, anticorps TMS-1, anticorps TNS1, anticorps masc, anticorps ARSC, anticorps ARSC1, anticorps ASC, anticorps ES, anticorps SSDD, anticorps XLI, anticorps PYD and CARD domain containing, anticorps steroid sulfatase, anticorps Pycard, anticorps STS, anticorps Sts

Sujet: Apoptosis is regulated by death domain (DD) and/or caspase recruitment domain (CARD) containing molecules and a caspase family of proteases.CARD containing cell death regulators include RAIDD, RICK, BCL10, Apaf-1, ARC, caspase-9, and caspase-2.A novel CARD domain containing protein was recently identified in human and mouse and designated ASC and TMS1.Ectopic expression of ASC/TMS1 induced apoptosis through activation of caspase-9 and inhibited the survival of human breast cancer cells (3, 4).Overexpression of ASC/TMS1 induced DNA fragmentation.ASC/TMS1 is expressed in a variety of human and mouse tissues.

Poids moléculaire: 25 kDa

Pathways: Steroid Hormone Biosynthesis, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity, Activated T Cell Proliferation