Arc anticorps (AA 2-18)

N° du produit ABIN1886849

L’anticorps Lapin Polyclonal anti-Arc a été validé pour WB et ELISA. Il convient pour détecter Arc dans des échantillons de Humain, Rat et Souris.

Aperçu rapide pour Arc anticorps (AA 2-18) (ABIN1886849)

Antigène: Arc (Activity-Regulated Cytoskeleton-Associated Protein (Arc))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Arc est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-Arc anticorps

Épitope: AA 2-18

Purification: Affinity chromatography purified via peptide column

Immunogène: Peptide corresponding to amino acids 2 to 18 of human origin these sequences are identical to those of human nuclear protein Nop30 (2) and differ from those of the rat homolog of ARC by one amino acid (3).

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Conseil sur la manipulation: Avoid freezing and thawing repeatly.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Détails sur Arc

Antigène: Arc (Activity-Regulated Cytoskeleton-Associated Protein (Arc))

Autre désignation: ARC

Sujet: Apoptosis is regulated by death domain (DD) and/or caspase recruitment domain (CARD) containing molecules and a caspase family of proteases.CARD containing cell death regulators include RAIDD, RICK BCL10, Apaf-1, caspase-9, and caspase-2.A novel CARD domain containing protein was recently identified and designated ARC for apoptosis repressor with CARD.ARC interacts with caspase-2 and -8 and inhibits enzymatic activity of caspase-8.ARC suppresses apoptosis induced by cell death adapters FADD and TRADD and by cell death receptors Fas, TNFR-1, and DR3.The messenger RNA of ARC is primarily expressed in skeletal muscle and cardiac tissue.
Synonyms: ARC

Poids moléculaire: 25 kDa

NCBI Accession: NP_003937