CIDEB anticorps (AA 204-219)

N° du produit ABIN1886856

Cet anticorps anti-CIDEB Polyclonal Lapin (ABIN1886856) détecte spécifiquement CIDEB dans ELISA et WB. L’anticorps est réactif avec des échantillons de Souris.

Aperçu rapide pour CIDEB anticorps (AA 204-219) (ABIN1886856)

Antigène: CIDEB (Cell Death-Inducing DFFA-Like Effector B (CIDEB))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CIDEB est non-conjugé

Application: ELISA, Western Blotting (WB)

Détail du produit anti-CIDEB anticorps

Épitope: AA 204-219

Réactivité croisée (Details): It has no cross activity to CIDE-A.

Purification: Affinity chromatography purified via peptide column

Immunogène: Peptide corresponding to amino acids 204 to 219 of murine CIDE-B.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Conseil sur la manipulation: Avoid freezing and thawing repeatly.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Détails sur CIDEB

Antigène: CIDEB (Cell Death-Inducing DFFA-Like Effector B (CIDEB))

Autre désignation: CIDE-B

Sujet: Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands.Cell death signals are transduced by death domain containing adapter molecules and members of the caspase family of proteases.These death signals finally cause the degradation of chromosomal DNA by activated DNase.DFF45/ICAD has been identified as inhibitor of caspase activated DNase DFF40/CAD.DFF45 related proteins CIDE-A and CIDE-B (for cell death-inducing DFF-like effector A and B) were recently identified.CIDE contains a new type of domain termed CIDE-N, which has high homology with the regulatory domains of DFF45/ICAD and DFF40/CAD.Expression of CIDE-B induces apoptosis, which is inhibited by DFF45.CIDE-B is a DFF45-inhibitable effector that promotes cell death and DNA fragmentation.CIDE-B is expressed mainly in liver and at lower levels in spleen, kidney, peripheral blood lymphocytes, and bone marrow.

Poids moléculaire: 25 kDa