DNASE2 anticorps (AA 347-360)
Aperçu rapide pour DNASE2 anticorps (AA 347-360) (ABIN1886871)
Antigène
Voir toutes DNASE2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 347-360
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Purification
- Affinity chromatography purified via peptide column
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Immunogène
- Peptide corresponding to amino acids 347 to 360 of human DNase II precursor (2-4).
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS containing 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
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Conseil sur la manipulation
- Avoid freezing and thawing repeatly.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store at 4 °C for short term use.Store at -20 °C for long term preservation.
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- DNASE2 (Deoxyribonuclease II, Lysosomal (DNASE2))
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Autre désignation
- DNase II
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Sujet
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Apoptosis is characterized by several morphological nuclear changes including chromatin condensation and nuclear fragmentation.These changes are triggered by the activation of members of caspase family, caspase activated DNase, and several novel proteins including AIF and Acinus.DNase II causes both chromatin condensation and DNA fragmentation.The genes encoding human, porcine, and murine DNase II have been cloned.The DNase II gene encodes a 40 kDa proenzyme.The mature enzyme consists of two non-identical subunits, the 32 kDa (alpha) and 12 kDa (beta) chains, generated by proteolytic processing.Overexpression of DNase II induces chromatin condensation.DNase II is ubiquitously expressed in human tissues.
Synonyms: DNase II -
Poids moléculaire
- 40 kDa
Antigène
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