DRAK2 anticorps (AA 351-365)

N° du produit ABIN1886873

L’anticorps anti-DRAK2 Polyclonal Lapin est utilisé pour la détection de DRAK2 dans des échantillons de Humain. Il a été validé pour ELISA, WB et ICC.

Aperçu rapide pour DRAK2 anticorps (AA 351-365) (ABIN1886873)

Antigène: DRAK2 (STK17B) (serine/threonine Kinase 17b (STK17B))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DRAK2 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunocytochemistry (ICC)

Détail du produit anti-DRAK2 anticorps

Épitope: AA 351-365

Réactivité croisée (Details): It has no cross responses to DAP or ZIP kinases. The approximately 70 kDa band is probably non-related to DRAK2 although it is peptide blockable.

Purification: Ion exchange chromatography purified

Immunogène: Peptide corresponding to amino acids 351 to 365 of human DRAK2.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Conseil sur la manipulation: Avoid freezing and thawing repeatly.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Détails sur DRAK2

Antigène: DRAK2 (STK17B) (serine/threonine Kinase 17b (STK17B))

Autre désignation: DRAK2

Sujet: Apoptosis is mediated by death domain containing adapter molecules and a caspase family of proteases.Certain serine/threonine protein kinases, such as ASK-1 and RIP, are mediators of apoptosis.Two novel serine/threonine kinases that induce apoptosis were recently identified and designated DRAK1 and DRAK2 (for DAP kinase-related apoptosis-inducing protein kinases).DRAKs contain an N-terminal kinase domain and a C-terminal regulation domain.Overexpression of DRAK2 induces apoptosis.DRAKs have high sequence homology to DAP and ZIP kinases, and they represent a novel family of serine/threonine kinases, which mediates apoptosis through their catalytic activities.DRAK2 is located in nucleus and the messenger RNA was ubiquitously expressed in human tissues.