MPRIP anticorps (AA 473-486)

N° du produit ABIN1886882

L’anticorps anti-MPRIP Polyclonal Lapin est utilisé pour la détection de MPRIP dans des échantillons de Souris et Rat. Il a été validé pour WB, IHC et ELISA.

Aperçu rapide pour MPRIP anticorps (AA 473-486) (ABIN1886882)

Antigène: MPRIP (Myosin Phosphatase rho Interacting Protein (MPRIP))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MPRIP est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Détail du produit anti-MPRIP anticorps

Épitope: AA 473-486

Purification: Affinity chromatography purified via peptide column

Immunogène: Peptide corresponding to amino acids 473 to 486 of murine RIP3.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Conseil sur la manipulation: Avoid freezing and thawing repeatly.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Détails sur MPRIP

Antigène: MPRIP (Myosin Phosphatase rho Interacting Protein (MPRIP))

Autre désignation: RIP3

Sujet: Certain serine/threonine protein kinases, such as ASK1, RIP, DAP, and ZIP kinases, are mediators of apoptosis.Receptor interacting proteins including RIP and RIP2/RICK mediate apoptosis induced by TNFR1 and Fas, two prototype members in the death receptor family.A novel member in the RIP kinase family was recently identified and designated RIP3.RIP3 contains N-terminal kinase domain but, unlike RIP or RIP2, lacks the C-terminal death or CARD domain.RIP3 binds to RIP and TNFR1, mediates TNFR1 induced apoptosis, and attenuates RIP and TNFR1 induced NF-kappaB activation.Overexpression of RIP3 induces apoptosis and NF-kappaB activation.The messenger RNA of RIP3 is expressed in a subset of adult tissues.

Poids moléculaire: 57 kDa