CARD9 anticorps (AA 521-536)

N° du produit ABIN1886886

Cet anticorps anti-CARD9 Polyclonal Lapin (ABIN1886886) détecte spécifiquement CARD9 dans WB, ELISA et ICC. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour CARD9 anticorps (AA 521-536) (ABIN1886886)

Antigène: CARD9 (Caspase Recruitment Domain Family, Member 9 (CARD9))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CARD9 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Détail du produit anti-CARD9 anticorps

Épitope: AA 521-536

Purification: Affinity chromatography purified via peptide column

Immunogène: Synthetic peptide corresponding to amino acids 521 to 536 of human CARD9.The sequence is different from that of rat origin by two amino acids.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Conseil sur la manipulation: Avoid freezing and thawing repeatly.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Détails sur CARD9

Antigène: CARD9 (Caspase Recruitment Domain Family, Member 9 (CARD9))

Autre désignation: CARD9

Sujet: Apoptosis is related to many diseases and development.Cell death signals are transduced by death domain (DD), death effector domain (DED), and caspase recruitment domain (CARD) containing molecules.CARD containing proteins include some caspases, Apaf-1, CARD4, IAPs, RICK, ARC, RAIDD, BCL-10, and ASC.A novel CARD-containing protein was recently identified and designated CARD9, which interacts with the CARD activation domain of BCL-10.CARD9 associates with BCL-10 and forms a complex within cells.CARD9 induces apoptosis and activates NF-kappaB.CARD9 is an upstream activator of BCL-10 and NF-kappaB signaling.

Poids moléculaire: 59 kDa

Pathways: Activation of Innate immune Response