ZNF346 antibody is predicted to not cross-react with other ZNF family members. Three isoforms of ZNF346 are known to exist, this antibody will recognize the two longest isoforms
Purification
Affinity chromatography purified via peptide column
Immunogène
20 amino acid peptide near the carboxy terminus of human ZNF346.
ZKSCAN1
Reactivité: Humain, Souris, Rat, Boeuf (Vache)
WB
Hôte: Lapin
Polyclonal
unconjugated
Restrictions
For Research Use only
Format
Liquid
Buffer
PBS containing 0.02 % sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Conseil sur la manipulation
Avoid freezing and thawing repeatly.
Stock
4 °C/-20 °C
Stockage commentaire
Store at 4 °C for short term use.Store at -20 °C for long term preservation.
Antigène
ZKSCAN1
(Zinc Finger with KRAB and SCAN Domains 1 (ZKSCAN1))
Sujet
ZNF346, also known as JAZ (just another zinc-finger protein), is a nucleolar, zinc finger protein which preferentially binds to double-stranded (ds) RNA or RNA/DNA hybrids with high affinity via C2H2 zinc fingers.ZNF346 contains four CH-type zinc finger motifs that are connected by long (28-38) amino acid linker sequences.ZNF346 is expressed in all tissues tested and localizes to the nucleus, primarily the nucleolus.ZNF346 is exported by exportin-5 but translocates back into nuclei by a facilitated diffusion mechanism.ZNF346 interacts with ILF3 in an RNA-independent manner and may be involved in cell growth and survival. Synonyms: Zinc finger protein 346, Just another zinc finger protein, JAZ