PD-1 anticorps (Center)
Aperçu rapide pour PD-1 anticorps (Center) (ABIN1887599)
Antigène
Voir toutes PD-1 (PDCD1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Center
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Purification
- Affinity chromatography purified via peptide column
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Immunogène
- 16 amino acid peptide from near the center of human PD-1.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS containing 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
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Conseil sur la manipulation
- Avoid freezing and thawing repeatly.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store at 4 °C for short term use.Store at -20 °C for long term preservation.
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- PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))
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Autre désignation
- PD-1
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Sujet
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Cell-mediated immune responses are initiated by T lymphocytes that are themselves stimulated by cognate peptides bound to MHC molecules on antig en-presenting cells (APC).T-cell activation is generally self-limited as activated T cells express receptors such as PD-1 (also known as PDCD-1) that mediate inhibitory signals from the APC.PD-1 can bind two different but related ligands, PDL-1 and PDL-2.Upon binding to either of these ligands, signals generated by PD-1 inhibit the activation of the immune response in the absence of
Synonyms: Programmed cell death 1, PDCD1, CD279 -
UniProt
- Q15116
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Pathways
- Cancer Immune Checkpoints
Antigène
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