CEP164 anticorps (N-Term)

N° du produit ABIN1888154

L’anticorps anti-CEP164 Polyclonal Lapin est utilisé pour la détection de CEP164 dans des échantillons de Humain, Rat et Souris. Il a été validé pour WB, ELISA et IHC.

Aperçu rapide pour CEP164 anticorps (N-Term) (ABIN1888154)

Antigène: CEP164 (Centrosomal Protein 164kDa (CEP164))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CEP164 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-CEP164 anticorps

Épitope: N-Term

Purification: Affinity chromatography purified via peptide column

Immunogène: CEP164 antibody was raised against an 18 amino acid peptide near the amino terminus of human CEP164.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Conseil sur la manipulation: Avoid freezing and thawing repeatly.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Détails sur CEP164

Antigène: CEP164 (Centrosomal Protein 164kDa (CEP164))

Autre désignation: CEP164

Sujet: CEP164 was initially identified as a centrosomal protein, but other studies have indicated that it also plays a role in the formation of primary cilia, the microtubule-based sensory antennae projecting from the surface of many eukaryotic cells as well as in DNA damage response acting as a mediator protein.CEP164 interacts with both ATR and ATM, proteins that trigger a number of cellular responses including the initiation of DNA damaged-induced cell cycle checkpoints.It is phosphorylated upon replication stress, ultraviolet (UV) radiation, and ionizing radiation, silencing of CEP164 significantly reduces the DNA damage-induced phosphorylation of several proteins in the DNA damage-activated signaling cascade and compromises cell survival after UV damage.At least two isoforms of CEP164 are known to exist.
Synonyms: Centrosomal protein 164

NCBI Accession: NP_055771

Pathways: M Phase