PAPPA anticorps

N° du produit ABIN191309

Détail du produit anti-PAPPA anticorps

Antigène: PAPPA (Pregnancy-Associated Plasma Protein A, Pappalysin 1 (PAPPA))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PAPPA est non-conjugé

Application: ELISA, Western Blotting (WB), Immunoprecipitation (IP), ELISA (Detection)

Specificité: Human PAPP-A antigen purified from placental blood (heterotetrameric complex, consisting of PAPP-A subunits and pro-MBP subunits). MAbs 11E4 and 5H9 are specific to proMBP subunit. IgG for MAb 11E4 IgG2a for MAbs 4G11, 10A5, 3C8, 10H9, 18A10 and 7A6 IgG2b for MAbs 5H9, 10E1 and 10E2

Réactivité croisée: Humain

Purification: Purified

Clone: 10H9

Isotype: IgG2a

Information d'application

Indications d'application: htPAPP-A and dPAPP-A (PAPP-A dimer) immunoassays and immunoprecipitation. Recommended pairs for the detection of dPAPP-A antigen in blood of AMI patients and patients with unstable angina (coating - conjugate): 4G11 – 3C8 4G11 – 10H9 10E1 – 7A6 Best pairs for the detection of htPAPP-A antigen in pregnancy serum (coating - conjugate): 4G11 – 3C8 4G11 – 10H9 10E2 – 10E1 10E2 – 5H9 5H9 – 10E2 10E1 – 7A6 PAPP-A immunodetection in Western blotting. MAb 18A10 recognizes PAPP-A subunit in reducing and non-reducing conditions after antigen transfer onto nitrocellulose membrane after SDS-gel electrophoresis. MAbs 4G11, 10A5, 18A10 and 10E1 recognize htPAPP-A, consisting of PAPP-A subunits and proMBP subunits, in non-reducing conditions.

Restrictions: For Research Use only

Stockage

Buffer: PBS, pH 7.4, 0.1 % sodium azide (NaN3) Material safety note: This product is sold as an antibody preparation for research use only. Standard Laboratory Practices should be followed when handling this material. Contains sodium azide (0.1 %) as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Références pour anticorps anti-PAPPA (ABIN191309)

Qin, Christiansen, Pettersson: "Point-of-care time-resolved immunofluorometric assay for human pregnancy-associated plasma protein A: use in first-trimester screening for Down syndrome." dans: Clinical chemistry, Vol. 48, Issue 3, pp. 473-83, (2002) (PubMed).

Détails sur PAPPA

Antigène: PAPPA (Pregnancy-Associated Plasma Protein A, Pappalysin 1 (PAPPA))

Autre désignation: Pappalysin-1 / PAPPA (PAPPA Produits)

Synonymes: anticorps 8430414N03Rik, anticorps IGFBP-4ase, anticorps PAG1, anticorps PAPP-A, anticorps ASBABP2, anticorps DIPLA1, anticorps PAPA, anticorps PAPPA1, anticorps Pappa, anticorps pappalysin 1, anticorps pregnancy-associated plasma protein A, anticorps PAPPA, anticorps Pappa, anticorps Pappa1