NPPB anticorps (N-Term)
Aperçu rapide pour NPPB anticorps (N-Term) (ABIN191931)
Antigène
Voir toutes NPPB AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 1-32, N-Term
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Specificité
- This antibody detects synthetic BNP (aa 1-32) and recombinant proBNP (aa 1-108).
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Purification
- Protein G chromatography
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Immunogène
- Synthetic human BNP (aa 1-32) KLH conjugatedAA Sequence: SPKMVQGSGCFGRKMDRISSSSGLGCKVLRRH
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Isotype
- IgG2b
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Indications d'application
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ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Reconstitution
- Restore in aqua bidest to 1 mg/mL.
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Buffer
- PBS pH 7,4
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Stock
- 4 °C/-20 °C
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Stockage commentaire
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Store lyophilized at 2 - 8 °C and reconstituted at -20 °C. Avoid repeated freezing andthawing.
Shelf life: One year from despatch. -
Date de péremption
- 12 months
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- NPPB (Natriuretic Peptides B (NPPB))
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Autre désignation
- Natriuretic Peptides B
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Sujet
- In cardiac tissue brain natriuretic peptide (BNP) is synthesized as 134 amino acid precursor (prepro-BNP), which is cleaved by proteases to form a 26 aa "signal" peptide and a 108 aa pro-BNP. Proteolytic digestion of pro-BNP results in formation of 76 aa amino-terminal NT-proBNP and biologically active 32 aa BNP hormone molecule. Both proBNP and NTproBNP circulate in human plasma and have been proposed as markers for early diagnosis of left ventricular dysfunction as well as prognostic markers of possible cardiac complications at patients with heart failure.
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ID gène
- 4879
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UniProt
- P16860
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Pathways
- Hormone Activity
Antigène
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