HLA-DP/DR anticorps (FITC)

N° du produit ABIN192205

Cet anticorps Souris Monoclonal détecte spécifiquement HLA-DP/DR dans FACS. Il présente une réactivité envers Humain et a été mentionné dans 1 publication.

Aperçu rapide pour HLA-DP/DR anticorps (FITC) (ABIN192205)

Antigène: HLA-DP/DR (MHC Class II HLA-DP/DR (HLA-DP/DR))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp HLA-DP/DR est conjugé à/à la FITC

Application: Flow Cytometry (FACS)

Clone: MEM-136

Détail du produit anti-HLA-DP/DR anticorps (FITC)

Fonction: Anti-HLA-DR/DP FITC

Specificité: The antibody MEM-136 recognizes a common extracellular epitope on beta-chain of human HLA-DR and HLA-DP. It reacts with alpha/beta dimer as well as with dissociated beta-subunit. DR and DP are the isotypes of human MHC Class II molecules expressed on antigen-presenting cells (APC, dendritic cells, B lymphocytes, monocytes, macrophages).

Réactivité croisée (Details): Human

Purification: Purified antibody is conjugated with fluorescein isothiocyanate (FITC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Immunogène: PHA-activated peripheral blood lymphocytes.

Isotype: IgG1

Information d'application

Indications d'application: Flow cytometry: The reagent is designed for analysis of human blood cells using 20 μL reagent / 100 μL of whole blood or 10⁶ cells in a suspension. The content of a vial (2 ml) is sufficient for 100 tests.

Restrictions: For Research Use only

Stockage

Reconstitution: No reconstitution is necessary.

Buffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Do not freeze.
Avoid prolonged exposure to light.

Stock: 4 °C

Stockage commentaire: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Références pour anticorps anti-HLA-DP/DR (FITC) (ABIN192205)

Koch, Staffler, Hüttinger, Hilgert, Prager, Cerný, Steinlein, Majdic, Horejsí, Stockinger: "T cell activation-associated epitopes of CD147 in regulation of the T cell response, and their definition by antibody affinity and antigen density." dans: International immunology, Vol. 11, Issue 5, pp. 777-86, (1999) (PubMed).

Détails sur HLA-DP/DR

Antigène: HLA-DP/DR (MHC Class II HLA-DP/DR (HLA-DP/DR))

Autre désignation: HLA-DR/DP

Sujet: HLA-DR, a member of MHC class II glycoproteins, that bind intracellularly processed peptides and present them to the Th cells, is composed of 36 kDa alpha chain and 27 kDa beta chain, both anchored in the plasma membrane. Together with other MHC II molecules HLA-DR plays a central role in the immune system.