CD300a anticorps

N° du produit ABIN192408

Cet anticorps anti-CD300a est un anticorps Souris Monoclonal détectant CD300a dans WB et FACS. Adapté pour Humain.

Aperçu rapide pour CD300a anticorps (ABIN192408)

Antigène: CD300a (CD300A)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD300a est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS)

Clone: MEM-260

Détail du produit anti-CD300a anticorps

Fonction: Anti-Hu CD300a Purified

Specificité: The antibody MEM-260 reacts with an extracellular epitope of CD300a, a 60 kDa leukocyte transmembrane glycoprotein expressed on human granulocytes, monocytes, neutrophils, NK cells, mast cells and dendritic cells, 25 % of circulating T cells and 15 % of circulating B cells.

Réactivité croisée (Details): Human

Purification: Purified by protein-A affinity chromatography.

Pureté: > 95 % (by SDS-PAGE)

Immunogène: HPB human acute lymphoid leukemia cell line

Isotype: IgG1

Information d'application

Indications d'application: Flow cytometry: Recommended dilution: 2 μg/mL.
Western blotting: Positive material: HPB cell line, negative material: JURKAT human cell line, RAJI human cell line, non-reducing conditions.

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Do not freeze.

Stock: 4 °C

Stockage commentaire: Store at 2-8°C. Do not freeze.

Détails sur CD300a

Antigène: CD300a (CD300A)

Autre désignation: CD300a

Sujet: CD300a molecule,CD300a (CMRF-35H, IRp60) is a non-MHC-specific inhibitory receptor of immunoglobulin superfamily, which contains three immunoreceptor tyrosine-based inhibitory motifs (ITIMs) that associate with SH2-containing phosphatases SHP-1 and SHP-2. CD300a is expressed on many cell types including T cells, NK cells, neutrophils, eosinophils or mast cells. Its triggering inhibits activating signals such as those of IL5, GM-CSF or eotaxin, as well as supresses mast cell degranulation or NK cell cytotoxic activity.,IRC, CLM-8, IGSF12, CMRF35H

ID gène: 11314

UniProt: Q9UGN4

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process