NCF1 anticorps

N° du produit ABIN1944805

Cet anticorps Lapin Polyclonal détecte spécifiquement NCF1 dans WB et IF. Il présente une réactivité avec des échantillons de Humain. Il a été cité dans 4+ publications.

Aperçu rapide pour NCF1 anticorps (ABIN1944805)

Antigène: NCF1 (Neutrophil Cytosol Factor 1 (NCF1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NCF1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Détail du produit anti-NCF1 anticorps

Isotype: IgG1

Information d'application

Indications d'application: IF: 1:100. WB: 1:250-1:1000. WB: 1:250-1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Stock: 4 °C,-20 °C

Références pour anticorps anti-NCF1 (ABIN1944805)

Görlach, Lee, Roesler, Hopkins, Christensen, Green, Chanock, Curnutte: "A p47-phox pseudogene carries the most common mutation causing p47-phox- deficient chronic granulomatous disease." dans: The Journal of clinical investigation, Vol. 100, Issue 8, pp. 1907-18, (1997) (PubMed).

Rodaway, Teahan, Casimir, Segal, Bentley: "Characterization of the 47-kilodalton autosomal chronic granulomatous disease protein: tissue-specific expression and transcriptional control by retinoic acid." dans: Molecular and cellular biology, Vol. 10, Issue 10, pp. 5388-96, (1990) (PubMed).

Volpp, Nauseef, Donelson, Moser, Clark: "Cloning of the cDNA and functional expression of the 47-kilodalton cytosolic component of human neutrophil respiratory burst oxidase." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 86, Issue 18, pp. 7195-9, (1989) (PubMed).

Lomax, Leto, Nunoi, Gallin, Malech: "Recombinant 47-kilodalton cytosol factor restores NADPH oxidase in chronic granulomatous disease." dans: Science (New York, N.Y.), Vol. 245, Issue 4916, pp. 409-12, (1989) (PubMed).

Détails sur NCF1

Antigène: NCF1 (Neutrophil Cytosol Factor 1 (NCF1))

Autre désignation: p47 phox

Sujet: NCF2, NCF1, and a membrane bound cytochrome b558 are required for activation of the latent NADPH oxidase (necessary for superoxide production).

Poids moléculaire: 44652 Da

ID gène: 653361

UniProt: P14598

Pathways: Signalisation PI3K-Akt