HEXIM1 anticorps

N° du produit ABIN1944936

Détail du produit anti-HEXIM1 anticorps

Antigène: HEXIM1 (Hexamethylene Bis-Acetamide Inducible 1 (HEXIM1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HEXIM1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Isotype: IgG

Information d'application

Indications d'application: IF: 1:100. WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Stock: 4 °C,-20 °C

Références pour anticorps anti-HEXIM1 (ABIN1944936)

Wittmann, Wang, Montano: "Identification of a novel inhibitor of breast cell growth that is down-regulated by estrogens and decreased in breast tumors." dans: Cancer research, Vol. 63, Issue 16, pp. 5151-8, (2003) (PubMed).

Ouchida, Kusuhara, Shimizu, Hisada, Makino, Morimoto, Handa, Ohsuzu, Tanaka: "Suppression of NF-kappaB-dependent gene expression by a hexamethylene bisacetamide-inducible protein HEXIM1 in human vascular smooth muscle cells." dans: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 8, Issue 2, pp. 95-107, (2003) (PubMed).

Yik, Chen, Nishimura, Jennings, Link, Zhou: "Inhibition of P-TEFb (CDK9/Cyclin T) kinase and RNA polymerase II transcription by the coordinated actions of HEXIM1 and 7SK snRNA." dans: Molecular cell, Vol. 12, Issue 4, pp. 971-82, (2003) (PubMed).

Détails sur HEXIM1

Antigène: HEXIM1 (Hexamethylene Bis-Acetamide Inducible 1 (HEXIM1))

Autre désignation: HEXIM1 (HEXIM1 Produits)

Synonymes: anticorps HEXIM1, anticorps fd44h02, anticorps hexim, anticorps wu:fd44h02, anticorps zgc:162976, anticorps CLP1, anticorps EDG1, anticorps HIS1, anticorps MAQ1, anticorps 7330426E13Rik, anticorps CLP-1, anticorps Clp1, anticorps Clp-1, anticorps hexamethylene bisacetamide inducible 1, anticorps hexamethylene bis-acetamide inducible 1, anticorps hexamethylene bis-acetamide inducible 1 L homeolog, anticorps HEXIM1, anticorps hexim1, anticorps Hexim1, anticorps hexim1.L

Sujet: Transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor. In cooperation with 7SK snRNA sequesters P-TEFb in a large inactive 7SK snRNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation. May also regulate NF-kappa-B, ESR1, NR3C1 and CIITA-dependent transcriptional activity.

Poids moléculaire: 40623 Da

ID gène: 10614

UniProt: O94992