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Vitronectin anticorps (AA 1-310)

L’anticorps Souris Monoclonal anti-Vitronectin a été validé pour WB, ELISA, IHC et IHC (p). Il convient pour détecter Vitronectin dans des échantillons de Humain, Boeuf (Vache), Chien, Lapin et Cat.
N° du produit ABIN1948187

Aperçu rapide pour Vitronectin anticorps (AA 1-310) (ABIN1948187)

Antigène

Voir toutes Vitronectin (VTN) Anticorps
Vitronectin (VTN)

Reactivité

  • 110
  • 42
  • 42
  • 5
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Humain, Boeuf (Vache), Chien, Lapin, Cat

Hôte

  • 102
  • 26
  • 4
  • 1
  • 1
Souris

Clonalité

  • 90
  • 44
Monoclonal

Conjugué

  • 71
  • 12
  • 7
  • 6
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp Vitronectin est non-conjugé

Application

  • 85
  • 51
  • 51
  • 24
  • 22
  • 19
  • 15
  • 14
  • 13
  • 11
  • 6
  • 6
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone

6F212
  • Épitope

    • 15
    • 9
    • 6
    • 6
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-310

    Specificité

    Highly specific for vitronectin. There is no evidence for cross-reactivity with other connective tissue proteins (fibronectin, elastin, collagen, laminin). Cross-reacts with vitronectin from cat, dog, rabbit and to a lesser extent with cow. Epitope is located within a cyanogen bromide cleavage fragment comprising aa 1-310. Binds nearly as well to native vitronectin as to denatured. It interferes with vitronectin-inhibition of the lysis of terminal complement complexes (TCC) and it inhibits vitronectin binding of PAI-1.

    Purification

    Protein A/G purified

    Immunogène

    Human vitronectin purified from plasma by heparin-affinity chromatography.

    Type of Immunogen: Purified protein

    Isotype

    IgG1 kappa
  • Indications d'application

    Approved: ELISA (1:40000), IHC, IHC-P (10 μg/mL), WB (1:50)

    Usage: Suitable for use in ELISA, Western Blot. ELISA: 1:40,000. Western Blot: 1:50.

    Commentaires

    Target Species of Antibody: Human

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    Lot specific

    Buffer

    PBS,  pH 7.4, 15 mM sodium azide

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Avoid repeat freeze-thaw cycles.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
  • Antigène

    Vitronectin (VTN)

    Autre désignation

    VTN / Vitronectin

    Sujet

    Name/Gene ID: VTN
    Family: Matrix Protein

    Synonyms: VTN, Epibolin, Serum-spreading factor, VNT, S-protein, Somatomedin B, V75, VN, Complement S-protein, Serum spreading factor, Vitronectin

    ID gène

    7448

    Pathways

    Autophagy, Smooth Muscle Cell Migration
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