DAB1 anticorps (Tyr232)

N° du produit ABIN197508

Détail du produit anti-DAB1 anticorps

Antigène: DAB1 (Disabled Homolog 1 (Drosophila) (DAB1))

Épitope: Tyr232

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DAB1 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: Dab1 antibody detects endogenous levels of total Dab1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogène: The antiserum was produced against synthesized non-phosphopeptide derived from human Dab1around the phosphorylation site of tyrosine 232 (G-V-YP-D-V).

Information d'application

Indications d'application: Immunohistochemistry: 1: 50-1: 100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS (without Mg2+ and Ca2+), pH 7.4 containing 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Détails sur DAB1

Antigène: DAB1 (Disabled Homolog 1 (Drosophila) (DAB1))

Autre désignation: DAB1 (DAB1 Produits)

Sujet: Disruption of DAB 1 (Disable 1) results in aberrant migration of neurons during development and disorganization of laminar structures throughout the brain. Dab1 is thought to function as an adaptor molecule in signal transduction processes. It contains a protein protein interaction (PI) similar to the phosphotyrosine binding domain of the Shc oncoprotein, it is phosphorylated by the Src protein tyrosine kinase, and it binds to SH2 binding domains in a phosphotyrosine dependent manner. DAB1 acts downstream of reelin in a signalling pathway.Synonyms: Disabled homolog 1

ID gène: 1600

NCBI Accession: NP_066566

UniProt: O75553