HMGA2 anticorps (C-Term)

N° du produit ABIN1981306

Cet anticorps Lapin Polyclonal détecte spécifiquement HMGA2 dans WB et FACS. Il présente une réactivité envers Humain et a été mentionné dans 1 publication.

Aperçu rapide pour HMGA2 anticorps (C-Term) (ABIN1981306)

Antigène: HMGA2 (High Mobility Group AT-Hook 2 (HMGA2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HMGA2 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS)

Clone: RB21014

Détail du produit anti-HMGA2 anticorps

Épitope: AA 64-92, C-Term

Homologie: M

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This HMGA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 64-92 amino acids from the C-terminal region of human HMGA2.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. FC: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-HMGA2 (ABIN1981306)

Luo, Li, Ge, Mei, Zhao, Jiang, Geng, Li, Yao, Cao: "HMGA2 upregulation mediates Cd-induced migration and invasion in A549 cells and in lung tissues of mice." dans: Chemico-biological interactions, Vol. 277, pp. 1-7, (2017) (PubMed).

Détails sur HMGA2

Antigène: HMGA2 (High Mobility Group AT-Hook 2 (HMGA2))

Autre désignation: HMGA2

Sujet: This gene encodes a protein that belongs to the non-histone chromosomal high mobility group (HMG) protein family. HMG proteins function as architectural factors and are essential components of the enhancesome. This protein contains structural DNA-binding domains and may act as a transcriptional regulating factor. Identification of the deletion, amplification, and rearrangement of this gene that are associated with myxoid liposarcoma suggests a role in adipogenesis and mesenchymal differentiation. A gene knock out study of the mouse counterpart demonstrated that this gene is involved in diet-induced obesity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Poids moléculaire: 11832

ID gène: 8091

NCBI Accession: NP_003474, NP_003475

UniProt: P52926

Pathways: Positive Regulation of Response to DNA Damage Stimulus