CD101 anticorps (PE)

N° du produit ABIN1981894

Cet anticorps Souris Monoclonal détecte spécifiquement CD101 dans FACS. Il présente une réactivité envers Humain et a été mentionné dans 2+ publications.

Aperçu rapide pour CD101 anticorps (PE) (ABIN1981894)

Antigène: CD101

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD101 est conjugé à/à la PE

Application: Flow Cytometry (FACS)

Clone: BB27

Détail du produit anti-CD101 anticorps (PE)

Fonction: Anti-Hu CD101 PE

Specificité: The mouse monoclonal antibody BB27 recognizes an extracellular epitope of CD101, a 140 kDa disulfide-bonded homodimeric protein expressed on activated T cells, and some other cell types, such as granulocytes and cells of the monocyte/macropgage lineage.

Réactivité croisée (Details): Human

Purification: Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Immunogène: Human thymic clone B12

Isotype: IgG1

Information d'application

Indications d'application: Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 10⁶ cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.

Restrictions: For Research Use only

Stockage

Buffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Do not freeze. Avoid prolonged exposure to light.
Do not use after expiration date stamped on vial label.
Short-term exposure to room temperature should not affect the quality of the reagent. However, if reagent is stored under any conditions other than those specified, the conditions must be verified by the user.

Stock: 4 °C

Stockage commentaire: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Références pour anticorps anti-CD101 (PE) (ABIN1981894)

Grassi, Dezutter-Dambuyant, McIlroy, Jacquet, Yoneda, Imamura, Boumsell, Schmitt, Autran, Debré, Hosmalin: "Monocyte-derived dendritic cells have a phenotype comparable to that of dermal dendritic cells and display ultrastructural granules distinct from Birbeck granules." dans: Journal of leukocyte biology, Vol. 64, Issue 4, pp. 484-93, (1998) (PubMed).

Bagot, Martinel, Charue, Weill, Boulland, Wechsler, Freeman, Bensussan, Boumsell: "CD101 is expressed by skin dendritic cells. Role in T-lymphocyte activation." dans: Tissue antigens, Vol. 50, Issue 5, pp. 439-48, (1998) (PubMed).

Détails sur CD101

Antigène: CD101

Autre désignation: CD101

Sujet: CD101 Molecule,CD101 is a type I transmembrane glycoprotein, which forms disulfide-linked homodimers. It is expressed on activated T cells, as well as on granulocytes, monocytes, dendritic cells or mucosal T cells. It plays a major role in the activation of T cells by skin dendritic cells. Function of CD101 has not been fully elucidated, but in mice its knock-out results in liver autoimmune disease induced by Novosphingobium aromaticivorans.,IGSF2, V7, EWI-101

ID gène: 9398

UniProt: Q93033