DNMT3A anticorps (AA 680-902) (FITC)

N° du produit ABIN1992077

L’anticorps Lapin Polyclonal anti-DNMT3A a été validé pour WB et ELISA. Il convient pour détecter DNMT3A dans des échantillons de Humain.

Aperçu rapide pour DNMT3A anticorps (AA 680-902) (FITC) (ABIN1992077)

Antigène: DNMT3A (DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DNMT3A est conjugé à/à la FITC

Application: Western Blotting (WB), ELISA

Détail du produit anti-DNMT3A anticorps (FITC)

Épitope: AA 680-902

Fonction: DNMT3A Antibody, FITC conjugated

Purification: Protein G purified

Pureté: >95 %

Immunogène: Recombinant Human DNA (cytosine-5)-methyltransferase 3A protein (680-902AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working concentration should be determinde by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin^TM: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur DNMT3A

Antigène: DNMT3A (DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A))

Autre désignation: DNMT3A

Sujet:

Background: Required for genome-wide de novo methylation and is essential for the establishment of DNA methylation patterns during development. DNA methylation is coordinated with methylation of histones. It modifies DNA in a non-processive manner and also methylates non-CpG sites. May preferentially methylate DNA linker between 2 nucleosomal cores and is inhibited by histone H1. Plays a role in paternal and maternal imprinting. Required for methylation of most imprinted loci in germ cells. Acts as a transcriptional corepressor for ZNF238. Can actively repress transcription through the recruitment of HDAC activity

Aliases: DNA (cytosine 5) methyltransferase 3 alpha antibody, DNA (cytosine 5) methyltransferase 3A antibody, DNA (cytosine-5)-methyltransferase 3A antibody, DNA cytosine methyltransferase 3A2 antibody, DNA methyltransferase 3 alpha antibody, DNA methyltransferase 3a antibody, DNA methyltransferase HsaIIIA antibody, DNA MTase HsaIIIA antibody, DNM3A_HUMAN antibody, DNMT 3a antibody, DNMT antibody, Dnmt3a antibody, DNMT3A2 antibody, M.HsaIIIA antibody, MCMT antibody, OTTHUMP00000201149 antibody, TBRS antibody

UniProt: Q9Y6K1