Haptoglobin anticorps (FITC)
Aperçu rapide pour Haptoglobin anticorps (FITC) (ABIN1992508)
Antigène
Voir toutes Haptoglobin (HP) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Purification
- Caprylic Acid Ammonium Sulfate Precipitation
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Immunogène
- Recombinant rat Haptoglobin protein
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Isotype
- IgG
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Indications d'application
- Optimal working concentration should be determinde by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- 0.03 % Proclin 300, 53 % Glycerol, 0.01 M PBS, pH 7.4
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClinTM: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze.
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Stock
- -20 °C/-80 °C
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Stockage commentaire
- Upon delivery aliquot and store at -20 °C or -80 °C.
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- Haptoglobin (HP)
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Autre désignation
- Haptoglobin
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Sujet
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As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidely cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway?.Uncleaved haptoglogin, also known as zonulin, plays a role in intestinal permeability, allowing intercellular tight junction disassembly, and controlling the equilibrium between tolerance and immunity to non-self antigens.
Synonyms: Liver regeneration-related protein LRRG173, Zonulin,Hp,Ba1-647 -
UniProt
- P06866
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Pathways
- Transition Metal Ion Homeostasis
Antigène
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