Glyco Protein G anticorps

N° du produit ABIN1993838

L’anticorps Lapin Polyclonal anti- a été validé pour ELISA, WB et IHC. Il convient pour détecter dans des échantillons de Rabies Virus. Il y a 1 publication disponible.

Aperçu rapide pour Glyco Protein G anticorps (ABIN1993838)

Antigène: Glyco Protein G

Reactivité: Rabies Virus

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit

Purification: Caprylic Acid Ammonium Sulfate Precipitation

Immunogène: Recombinant Rabies virus Glycoprotein G protein

Isotype: IgG

Information d'application

Indications d'application: Optimal working concentration should be determinde by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 0.03 % Proclin 300, 53 % Glycerol, 0.01 M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin^TM: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze.

Stock: -20 °C/-80 °C

Stockage commentaire: Upon delivery aliquot and store at -20 °C or -80 °C.

Référence

Starodubova, Kuzmenko, Pankova, Latanova, Preobrazhenskaya, Karpov: "[A DNA Construct That Encodes the Rabies Virus Consensus Glycoprotein with a Proteasome Degradation Signal Induces Antibody Production with IgG2A Subtype Predominance]." dans: Molekuliarnaia biologiia, Vol. 52, Issue 3, pp. 527-532, (2018) (PubMed).

Détail du antigène

Antigène: Glyco Protein G

Classe de substances: Viral Protein

Sujet: Attaches the virus to host cellular receptor, inducing endocytosis of the virion. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell membrane. There is convincing in vitro evidence that the muscular form of the nicotinic acetylcholine receptor (nAChR), the neuronal cell adhesion molecule (NCAM), and the p75 neurotrophin receptor (p75NTR) bind glycoprotein G and thereby facilitate rabies virus entry into cells.
Synonyms: G

UniProt: P03524