Rabies Virus Nucleoprotein (RABV N) anticorps (Biotin)

N° du produit ABIN1993846

Cet anticorps Lapin Polyclonal détecte spécifiquement dans ELISA et WB. Il présente une réactivité envers Rabies Virus.

Aperçu rapide pour Rabies Virus Nucleoprotein (RABV N) anticorps (Biotin) (ABIN1993846)

Antigène: Rabies Virus Nucleoprotein (RABV N)

Reactivité: Rabies Virus

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Biotin

Application: ELISA, Western Blotting (WB)

Détail du produit

Purification: Caprylic Acid Ammonium Sulfate Precipitation

Immunogène: Recombinant Rabies virus Nucleoprotein protein

Isotype: IgG

Information d'application

Indications d'application: Optimal working concentration should be determinde by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 0.03 % Proclin 300, 53 % Glycerol, 0.01 M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin^TM: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze.

Stock: -20 °C/-80 °C

Stockage commentaire: Upon delivery aliquot and store at -20 °C or -80 °C.

Détail du antigène

Antigène: Rabies Virus Nucleoprotein (RABV N)

Autre désignation: Rabies Virus Nucleoprotein

Classe de substances: Influenza Protein

Sujet: Encapsidates the genome in a ratio of one protein N per nine ribonucleotides, protecting it from nucleases. If expressed without protein P it binds non-specifically RNA and therefore can bind it\'s own mRNA. Interaction with protein P abolishes any non-specific RNA binding, and prevents phosphorylation. The soluble N-P complex encapsidates specifically the genomic RNA, with protein N protecting the genome like a pearl necklace. The encapsidated genomic RNA is termed the nucleocapsid (NC) and serves as template for viral transcription and replication. Protein N binds protein P in the NC through a different interaction, and can be phosphorylated. Subsequent viral replication is dependent on intracellular concentration of newly synthesized protein N. During replication, encapsidation by protein N is coupled to RNA synthesis and all replicative products are resistant to nucleases
Synonyms: NP, Nucleocapsid protein, Protein N, N

UniProt: P15197