RYR1 anticorps (AA 1-534) (FITC)
Aperçu rapide pour RYR1 anticorps (AA 1-534) (FITC) (ABIN1993994)
Antigène
Voir toutes RYR1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1-534
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Réactivité croisée
- Humain
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Purification
- >95%, Protein G purified
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Immunogène
- Recombinant Human Ryanodine receptor 1 protein (1-534AA)
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Isotype
- IgG
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Indications d'application
- Optimal working concentration should be determinde by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClinTM: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze.
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- RYR1 (Ryanodine Receptor 1 (Skeletal) (RYR1))
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Autre désignation
- RYR1
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Sujet
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Background: Calcium channel that mediates the release of Ca2+ from the sarcoplasmic reticulum into the cytoplasm and thereby plays a key role in triggering muscle contraction following depolarization of T-tubules. Repeated very high-level exercise increases the open probability of the channel and leads to Ca2+ leaking into the cytoplasm. Can also mediate the release of Ca2+ from intracellular stores in neurons, and may thereby promote prolonged Ca2+ signaling in the brain. Required for normal embryonic development of muscle fibers and skeletal muscle. Required for normal heart morphogenesis, skin development and ossification during embryogenesis
Aliases: CCO antibody, Central core disease of muscle antibody, MHS antibody, MHS1 antibody, PPP1R137 antibody, Protein phosphatase 1 regulatory subunit 137 antibody, Ryanodine receptor 1 antibody, RYDR antibody, RYR antibody, RYR-1 antibody, RyR1 antibody, RYR1_HUMAN antibody, sarcoplasmic reticulum calcium release channel antibody, Skeletal muscle calcium release channel antibody, Skeletal muscle ryanodine receptor antibody, Skeletal muscle-type ryanodine receptor antibody, SKRR antibody, Type 1 ryanodine receptor antibody
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UniProt
- P21817
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Pathways
- Myometrial Relaxation and Contraction, Skeletal Muscle Fiber Development
Antigène
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