L-Selectin anticorps (FITC)
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- Antigène Voir toutes L-Selectin (SELL) Anticorps
- L-Selectin (SELL) (Selectin L (SELL))
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Reactivité
- Humain, Boeuf (Vache), Cynomolgus, Macaque rhésus
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp L-Selectin est conjugé à/à la FITC
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Application
- Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Specificité
- Recognizes human CD62L, also known a L-selectin, a 74-95kD member of the selectin family of adhesion receptors, which acts as a ligand for both CD62-P (P-selectin) and CD62E (E-selectin). Human CD62L is constitutively expressed on most leucocytes including monocytes, granulocytes, lymphocytes, NK cells, bone marrow myeloid progenitor cells and on a subset of thymocytes. CD62L plays an important role in leucocyte tethering and rolling on the endothelial cell surface and for the homing of naA-ve lymphocytes to lymph nodes and Peyers patches via HEV. Neutrophils require a constant supply of this molecule on the cell surface for migration into peripheral tissues and adhesion to activated endothelium at sites of inflammation, where CD62L is rapidly shed as soluble L-selectin, but surface expression still remains. The expression of CD62L is down regulated on lymphocytes and neutrophils by PMA stimulation.
- Purification
- Protein G purified
- Immunogène
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PHA stimulated lymphoblasts.
Type of Immunogen: Cells - Clone
- FMC46
- Isotype
- IgG2b
- Top Product
- Discover our top product SELL Anticorps primaire
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- Indications d'application
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Approved: Flo (1:1), IHC, IHC-Fr, IP
Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. Flow Cytometry: Use 10 μL of the suggested working dilution to label 10^6 cells or 100 μL whole blood. Method sheets are available on request. - Commentaires
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Target Species of Antibody: Human
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- PBS, pH 7.4, 0.09 % sodium azide, 1 % BSA.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- Antigène
- L-Selectin (SELL) (Selectin L (SELL))
- Autre désignation
- SELL / L-Selectin / CD62L (SELL Produits)
- Synonymes
- anticorps CD62L, anticorps LAM1, anticorps LECAM1, anticorps LEU8, anticorps LNHR, anticorps LSEL, anticorps LYAM1, anticorps PLNHR, anticorps TQ1, anticorps A.11, anticorps L-selectin, anticorps LECAM-1, anticorps SELE, anticorps AI528707, anticorps Lnhr, anticorps Ly-22, anticorps Ly-m22, anticorps Lyam-1, anticorps Lyam1, anticorps selectin L, anticorps selectin, lymphocyte, anticorps SELL, anticorps Sell
- Classe de substances
- Chemical
- Sujet
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Name/Gene ID: SELL
Synonyms: SELL, CD62L, CD62L antigen, LAM-1, LAM1, LECAM1, LEU8, Leukocyte adhesion molecule 1, Lyam-1, LSEL, gp90-MEL, HLHRc, PLNHR, L-selectin, Leu-8, Selectin L, LNHR, LYAM1, Lymph node homing receptor, Lymphocyte adhesion molecule 1, TQ1, Pln homing receptor - ID gène
- 6402
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