MADCAM1 anticorps (Biotin)

N° du produit ABIN206532

Cet anticorps anti-MADCAM1 Monoclonal Souris conjugué à Biotin (Clone 314G8) (ABIN206532) détecte spécifiquement MADCAM1 dans ELISA et FACS. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour MADCAM1 anticorps (Biotin) (ABIN206532)

Antigène: MADCAM1 (Mucosal Vascular Addressin Cell Adhesion Molecule 1 (MADCAM1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp MADCAM1 est conjugé à/à la Biotin

Application: ELISA, Flow Cytometry (FACS)

Clone: 314G8

Détail du produit anti-MADCAM1 anticorps (Biotin)

Specificité: Recognizes human mucosal addressin cell adhesion molecule 1 (MAdCAM-1), a 60kD cell surface protein that is involved in lymphocyte trafficking. MAdCAM-1 is expressed on high endothelial venules of Peyers patches and mesenteric lymph nodes. MAdCAM-1 expression has also been reported in the gut lamina propria but clone 314G8 does not recognize MAdCAM-1 in these tissues. Clone Reacts with the ligand-binding first Ig domain and reports suggest that a splice variant exists in the gut which is not recognized by clone 314G8. Clone 314G8 is reported to block the interaction of MAdCAM-1 with alpha 4 beta 7. XXX recommend the use of MCA2320EL for this purpose.

Purification: Protein G purified

Immunogène: Recombinant soluble MAdCAM-1-fc fusion protein.

Type of Immunogen: Fusion protein

Isotype: IgG1

Information d'application

Indications d'application: Approved: ELISA (1 - 10 μg/mL), Flo (1:1 - 1:10)

Usage: Flow Cytometry: Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL. Method sheets are available on request. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.4, 0.09 % sodium azide, 1 % BSA.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: 4°C or -20°C, Avoid freeze-thaw cycles.

Détails sur MADCAM1

Antigène: MADCAM1 (Mucosal Vascular Addressin Cell Adhesion Molecule 1 (MADCAM1))

Autre désignation: MAdCAM-1

Sujet: Name/Gene ID: MADCAM1

Synonyms: MADCAM1, HMAdCAM-1, MACAM1, MAdCAM-1

ID gène: 8174