MADCAM1 anticorps (Biotin)
Aperçu rapide pour MADCAM1 anticorps (Biotin) (ABIN206532)
Antigène
Voir toutes MADCAM1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- Recognizes human mucosal addressin cell adhesion molecule 1 (MAdCAM-1), a 60kD cell surface protein that is involved in lymphocyte trafficking. MAdCAM-1 is expressed on high endothelial venules of Peyers patches and mesenteric lymph nodes. MAdCAM-1 expression has also been reported in the gut lamina propria but clone 314G8 does not recognize MAdCAM-1 in these tissues. Clone Reacts with the ligand-binding first Ig domain and reports suggest that a splice variant exists in the gut which is not recognized by clone 314G8. Clone 314G8 is reported to block the interaction of MAdCAM-1 with alpha 4 beta 7. XXX recommend the use of MCA2320EL for this purpose.
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Purification
- Protein G purified
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Immunogène
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Recombinant soluble MAdCAM-1-fc fusion protein.
Type of Immunogen: Fusion protein -
Isotype
- IgG1
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Indications d'application
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Approved: ELISA (1 - 10 μg/mL), Flo (1:1 - 1:10)
Usage: Flow Cytometry: Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL. Method sheets are available on request. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. -
Commentaires
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Target Species of Antibody: Human
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- PBS, pH 7.4, 0.09 % sodium azide, 1 % BSA.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- 4°C or -20°C, Avoid freeze-thaw cycles.
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- MADCAM1 (Mucosal Vascular Addressin Cell Adhesion Molecule 1 (MADCAM1))
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Autre désignation
- MAdCAM-1
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Sujet
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Name/Gene ID: MADCAM1
Synonyms: MADCAM1, HMAdCAM-1, MACAM1, MAdCAM-1 -
ID gène
- 8174
Antigène
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