Complement C3d anticorps

N° du produit ABIN206658

Cet anticorps anti-Complement C3d est un anticorps Souris Monoclonal détectant Complement C3d dans WB, IHC, IHC (fro), FACS et ELISA. Adapté pour Humain.

Aperçu rapide pour Complement C3d anticorps (ABIN206658)

Antigène: Complement C3d (C3d) (Complement Fragment 3d (C3d))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Complement C3d est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Flow Cytometry (FACS), ELISA

Détail du produit anti-Complement C3d anticorps

Specificité: Specific for human complement component 3d (C3d), a 33kD polypeptide fragment generated over the course of complement activation where complement 3 (C3) convertases cleave C3 to C3b, which is further degraded into iC3b and C3dg/C3d. C3d is involved in the regulation of many aspects of the immune response, including antigen processing and presentation. The C3d/antigen complex mediates B cell activation by simultaneously binding antigen-specific surface bound immunoglobulin and CD21, lowering the complement activation threshold. C3 is crucial in the induction of tolerance generated when an antigen is introduced into immunoprivileged sites and this is exploited by pathogens and cancer cells to evade the immune system by inhibiting complement activation.

Purification: Protein A purified

Immunogène: Purified C3d from human plasma.

Isotype: IgG1

Information d'application

Indications d'application: Approved: ELISA, Flo, IHC, IHC-Fr, WB (1:5000)

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Borate buffered saline, 0.1 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: avoid freeze thaw cycles. Store undiluted.

Stock: 4 °C,-20 °C

Stockage commentaire: Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles. Store undiluted.

Détails sur Complement C3d

Antigène: Complement C3d (C3d) (Complement Fragment 3d (C3d))

Autre désignation: Complement C3d

UniProt: P01024