Retinoblastoma Protein (Rb) anticorps (Cleavage Site)
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- Antigène Voir toutes Retinoblastoma Protein (Rb) (Rb Protein) Anticorps
- Retinoblastoma Protein (Rb) (Rb Protein) (Retinoblastoma Protein (Rb Protein))
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Épitope
- Cleavage Site
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Reactivité
- Humain, Souris
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp Retinoblastoma Protein (Rb) est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Specificité
- Recognizes cleaved Rb (DRb-p70). Does not recognize full-length Rb. In camptothecin treated HL60, an ~68 kD band is observed. DRb-p70 exists in vivo as an N-terminally truncated form of Rb (Liu et al.). DRb-p70 is thought to be the product of alternative translation and is expressed in primary myeloid cells in fetal liver, bone marrow and spleen. DRb-p70 is also specifically expressed in tumor-associated macrophages (TAMs). TAMs are an important targets of cancer therapy. DRb-p70 is a marker of TAMs, and maybe useful for identifying tumors with macrophage infiltration (Liu et al, 2005).
- Purification
- Protein G purified
- Immunogène
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A synthetic peptide corresponding to a region of the caspase-3-induced cleavage site of human Rb.
Type of Immunogen: Synthetic peptide - Clone
- 172C1094
- Isotype
- IgG1
- Top Product
- Discover our top product Rb Protein Anticorps primaire
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anti-Retinoblastoma Protein (Rb Protein) (AA 858-886) antibody
Rb Protein Reactivité: Humain WB, ELISA, IHC, FACS Hôte: Lapin Polyclonal unconjugated
anti-Retinoblastoma Protein (Rb Protein) (pSer811) antibodyRb Protein Reactivité: Humain ELISA, IHC, IF, DB Hôte: Lapin Polyclonal unconjugated
anti-Retinoblastoma Protein (Rb Protein) (AA 586-615) antibodyRb Protein Reactivité: Humain WB, ELISA, IHC, IF Hôte: Lapin Polyclonal unconjugated
anti-Retinoblastoma Protein (Rb Protein) (pSer608) antibodyRb Protein Reactivité: Humain ELISA, IHC, DB Hôte: Lapin Polyclonal unconjugated
anti-Retinoblastoma Protein (Rb Protein) (pSer780) antibodyRb Protein Reactivité: Humain ELISA, IHC, DB Hôte: Lapin Polyclonal unconjugated
anti-Retinoblastoma Protein (Rb Protein) (pSer788) antibodyRb Protein Reactivité: Humain ELISA, IHC, DB Hôte: Lapin Polyclonal unconjugated
anti-Retinoblastoma Protein (Rb Protein) antibodyRb Protein Reactivité: Humain ELISA, IHC Hôte: Souris Monoclonal 7E4B8 unconjugated
anti-Retinoblastoma Protein (Rb Protein) (AA 251-268) antibodyRb Protein Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Singe, Porc, Cheval, Roussette (Chauve-souris) WB Hôte: Lapin Polyclonal unconjugated
anti-Retinoblastoma Protein (Rb Protein) (N-Term) antibodyRb Protein Reactivité: Humain, Souris, Singe WB Hôte: Lapin Polyclonal unconjugated
anti-Retinoblastoma Protein (Rb Protein) (C-Term) antibodyRb Protein Reactivité: Humain, Boeuf (Vache), Chien, Porc, Roussette (Chauve-souris), Cobaye WB Hôte: Lapin Polyclonal unconjugated
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- Indications d'application
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Approved: IHC, WB (2 μg/mL)
Not recommended for: IHC-P - Commentaires
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Target Species of Antibody: Human
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- PBS, 0.02 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-80 °C
- Stockage commentaire
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Short term: 4°C
Long term: -70°C.
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- Antigène
- Retinoblastoma Protein (Rb) (Rb Protein) (Retinoblastoma Protein (Rb Protein))
- Autre désignation
- RB1 / Retinoblastoma / RB (Rb Protein Produits)
- Sujet
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Name/Gene ID: RB1
Synonyms: RB1, p105-Rb, Osteosarcoma, PRb, Retinoblastoma, Retinoblastoma 1, OSRC, RB, Pp110 - ID gène
- 5925
- UniProt
- P06400
- Pathways
- Mitotic G1-G1/S Phases
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