Transferrin anticorps (N-Term)

N° du produit ABIN211539

Cet anticorps anti-Transferrin est un anticorps Souris Monoclonal détectant Transferrin dans ELISA, IF et Func. Adapté pour Humain, Porc et Lapin.

Aperçu rapide pour Transferrin anticorps (N-Term) (ABIN211539)

Antigène: Transferrin (TF)

Reactivité: Humain, Porc, Lapin

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Transferrin est non-conjugé

Application: ELISA, Immunofluorescence (IF), Functional Studies (Func)

Détail du produit anti-Transferrin anticorps

Épitope: N-Term

Specificité: Anti transferrin clone HTF-14 is specific for the N-terminal domain of human transferrin and has been shown to block binding of transferrin to the transferrin receptor (CD71). Clone HTF-14 is not able to recognize receptor bound transferrin. Clone HTF-14 recognizes a conformational epitope in a loop of the N lobe of transferrin involving the critical Lys-144 residue, also essential for binding of the N lobe to the transferrin receptor Transferrin is a 77 kD plasma protein synthesized by the liver involved with the transport of iron. Each transferrin molecule has two domains, both with facility to carry 2 ferric ions. The iron/transferrin complex is essential for haemoglobin synthesis and certain types of cell division.

Aucune reactivité croisée: Boeuf (Vache), Mouton, Chien, Cheval

Purification: Protein A purified

Immunogène: Purified porcine transferrin ( N-TERMINAL ).

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.2, 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Détails sur Transferrin

Antigène: Transferrin (TF)

Autre désignation: TF / Transferrin

Sujet: Name/Gene ID: TF

Synonyms: TF, PRO1557, Serotransferrin, Siderophilin, TFQTL1, Beta-1 metal-binding globulin, Transferrin, PRO2086

ID gène: 7018

UniProt: P02787

Pathways: Transition Metal Ion Homeostasis