CD81 anticorps

N° du produit ABIN212888

L’anticorps Hamster Monoclonal anti-CD81 a été validé pour FACS. Il convient pour détecter CD81 dans des échantillons de Souris.

Aperçu rapide pour CD81 anticorps (ABIN212888)

Antigène: CD81

Reactivité: Souris

Hôte: Hamster

Clonalité: Monoclonal

Conjugué: Cet anticorp CD81 est non-conjugé

Application: Flow Cytometry (FACS)

Clone: Eat2

Détail du produit anti-CD81 anticorps

Specificité: Reacts with the extracellular loops of murine CD81 (TAPA-1) molecule. As a member of the tetraspanin superfamily of cell-surface proteins, CD81 has been linked to the control of cell proliferation, adhesion and motility. CD81 is expressed in higher levels on resting murine B cells than on resting T cells and is functionally active on B cells as it induces homotypic adhesion of B lymphocytes. Unlike human CD81, which is expressed equally on all thymocytes, murine CD81 is upregulated on CD4+CD8+ thymocytes, then down-regulated again on mature single-positive thymocytes. Murine dendritic cells, splenic macrophages and non-killer cells all express very high levels of CD81. CD81 has also been involved in the induction of IL-4 secretion from T cells during Th2 immune responses. It has been reported that CD81 expression can also be induced in mature T cells upon activation. This anti-CD81 mAb has been shown to decrease the proliferation of LPS stimulated CD81+/+ B cells to levels similar to that of CD81-/- B cells.

Purification: Protein G purified

Immunogène:

Type of Immunogen: Native protein

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

Target Species of Antibody: Mouse

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for short term applications. For long term storage, aliquot and store at -20°C.

Détails sur CD81

Antigène: CD81

Autre désignation: CD81

Sujet: Name/Gene ID: CD81
Family: Tetraspan

Synonyms: CD81, CD81 antigen, CD81 Molecule, CVID6, S5.7, TAPA1, TAPA-1, Tetraspanin-28, TSPAN28, Tspan-28

ID gène: 975

UniProt: P60033

Pathways: Inositol Metabolic Process, Hepatitis C