THRA anticorps (Ligand Binding Domain)

N° du produit ABIN213505

Cet anticorps Lapin Polyclonal détecte spécifiquement THRA dans IHC et IHC (p). Il présente une réactivité envers Humain et Singe.

Aperçu rapide pour THRA anticorps (Ligand Binding Domain) (ABIN213505)

Antigène: THRA (Thyroid Hormone Receptor, alpha (THRA))

Reactivité: Humain, Singe

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp THRA est non-conjugé

Application: Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-THRA anticorps

Épitope: Ligand Binding Domain

Marque: IHC-plus™

Specificité: Human THRA. BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Homologie: Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey (100%) Mouse, Rat, Sheep, Dog, Bovine, Hamster, Elephant, Panda, Rabbit, Horse, Pig (95%) Lizard (85%) Opossum (80%).

Purification: Immunoaffinity purified

Immunogène: Synthetic 20 amino acid peptide from ligand-binding domain of human THRA. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey (100%), Mouse, Rat, Sheep, Dog, Bovine, Hamster, Elephant, Panda, Rabbit, Horse, Pig (95%), Lizard (85%), Opossum (80%).

Type of Immunogen: Synthetic peptide

Information d'application

Indications d'application: Approved: IHC, IHC-P (10 - 15 μg/mL)

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 10 μg/mL.

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: PBS, less than 0.1 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.

Date de péremption: 12 months

Détails sur THRA

Antigène: THRA (Thyroid Hormone Receptor, alpha (THRA))

Autre désignation: THRA / THR Alpha

Sujet: Name/Gene ID: THRA
Subfamily: NR1 Thyroid hormone-like
Family: NHR

Synonyms: THRA, AR7, C-ERBA-1, C-erbaalpha, EAR-7.1/EAR-7.2, ERB-T-1, ERBA1, EAR-7, ERBA-related 7, HTR alpha 1, HTR alpha 2, THRA1, Thyroid hormone receptor alpha, T3R, Tralpha2, Triiodothyronine receptor, V-erbA-related protein 7, Thyroid hormone receptor, Tralpha1, NR1A1, THRA3, C-erbA-alpha, CHNG6, EAR7, ERBA, Erba-alpha, THRA2, TR alpha, Tralpha

ID gène: 7067

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Sensory Perception of Sound, Cellular Response to Molecule of Bacterial Origin, Regulation of Lipid Metabolism by PPARalpha, Regulation of Muscle Cell Differentiation, Maintenance of Protein Location, Skeletal Muscle Fiber Development