BAZ1A anticorps (PE)

N° du produit ABIN2169796

Cet anticorps Lapin Polyclonal détecte spécifiquement BAZ1A dans WB. Il présente une réactivité envers Humain, Rat et Souris.

Aperçu rapide pour BAZ1A anticorps (PE) (ABIN2169796)

Antigène: BAZ1A (Bromodomain Adjacent To Zinc Finger Domain, 1A (BAZ1A))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BAZ1A est conjugé à/à la PE

Application: Western Blotting (WB)

Détail du produit anti-BAZ1A anticorps (PE)

Réactivité croisée: Rat

Homologie: Human,Mouse,Dog,Cow,Pig,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human ATP utilizing chromatin assembly and remodeling factor 1

Isotype: IgG

Information d'application

Indications d'application: FCM: (1:20-100)
Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Détails sur BAZ1A

Antigène: BAZ1A (Bromodomain Adjacent To Zinc Finger Domain, 1A (BAZ1A))

Autre désignation: Acf1

Sujet:

Synonyms: BAZ1A, Acf1, ACF1, drosophila, homolog of antibody ATP dependent chromatin remodelling protein, ATP utilizing chromatin assembly and remodeling factor 1, ATP-dependent chromatin-remodeling protein, ATP-utilizing chromatin assembly and remodeling factor 1, Baz1a, BAZ1A_HUMAN, Bromodomain adjacent to zinc finger domain 1A, Bromodomain adjacent to zinc finger domain protein 1A, cbp146, CHRAC subunit ACF1, Gtl5.

Background: Component of the ACF complex, an ATP-dependent chromatin remodeling complex, that regulates spacing of nucleosomes using ATP to generate evenly spaced nucleosomes along the chromatin. The ATPase activity of the complex is regulated by the length of flanking DNA. Also involved in facilitating the DNA replication process. BAZ1A is the accessory, non-catalytic subunit of the complex which can enhance and direct the process provided by the ATPase subunit, SMARCA5, probably through targeting pericentromeric heterochromatin in late S phase. Moves end-positioned nucleosomes to a predominantly central position. May have a role in nuclear receptor-mediated transcription repression.Component of the histone-fold protein complex CHRAC complex which faciliates nucleosome sliding by the ACF complex and enhances ACF-mediated chromatin assembly. The C-terminal regions of both CHRAC1 and POLE1 are required for these functions.

ID gène: 11177

UniProt: Q9NRL2