PLA2G6 anticorps (PE)

N° du produit ABIN2172205

Cet anticorps Lapin Polyclonal détecte spécifiquement PLA2G6 dans WB. Il présente une réactivité envers Humain, Rat et Souris.

Aperçu rapide pour PLA2G6 anticorps (PE) (ABIN2172205)

Antigène: PLA2G6 (Phospholipase A2, Group VI (Cytosolic, Calcium-Independent) (PLA2G6))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PLA2G6 est conjugé à/à la PE

Application: Western Blotting (WB)

Détail du produit anti-PLA2G6 anticorps (PE)

Réactivité croisée: Rat

Homologie: Human,Mouse,Dog,Pig

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human CaI-PLA2/PLA2G6

Isotype: IgG

Information d'application

Indications d'application: FCM: (1:20-100)
Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Détails sur PLA2G6

Antigène: PLA2G6 (Phospholipase A2, Group VI (Cytosolic, Calcium-Independent) (PLA2G6))

Sujet:

Synonyms: GVI, PLA2, INAD1, NBIA2, iPLA2, NBIA2A, NBIA2B, PARK14, PNPLA9, CaI-PLA2, IPLA2-VIA, iPLA2beta, 85/88 kDa calcium-independent phospholipase A2, Group VI phospholipase A2, GVI PLA2, Intracellular membrane-associated calcium-independent phospholipase A2 beta, iPLA2-beta, Patatin-like phospholipase domain-containing protein 9, PLA2G6, PLPLA9

Background: Catalyzes the release of fatty acids from phospholipids. It has been implicated in normal phospholipid remodeling, nitric oxide-induced or vasopressin-induced arachidonic acid release and in leukotriene and prostaglandin production. May participate in fas mediated apoptosis and in regulating transmembrane ion flux in glucose-stimulated B-cells. Has a role in cardiolipin (CL) deacylation. Required for both speed and directionality of monocyte MCP1/CCL2-induced chemotaxis through regulation of F-actin polymerization at the pseudopods. Isoform ankyrin-iPLA2-1 and isoform ankyrin-iPLA2-2, which lack the catalytic domain, are probably involved in the negative regulation of iPLA2 activity.

ID gène: 8398

UniProt: O60733

Pathways: Positive Regulation of Peptide Hormone Secretion