Cited1/Abcc1 anticorps (PE)

N° du produit ABIN2173071

Cet anticorps anti-Cited1/Abcc1 Polyclonal Lapin conjugué à PE (ABIN2173071) détecte spécifiquement Cited1/Abcc1 dans WB. L’anticorps est réactif avec des échantillons de Rat, Humain et Souris.

Aperçu rapide pour Cited1/Abcc1 anticorps (PE) (ABIN2173071)

Antigène: Cited1/Abcc1

Reactivité: Rat, Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: PE

Application: Western Blotting (WB)

Détail du produit

Specificité: May cross react with CITED2

Réactivité croisée: Rat

Homologie: Human,Mouse,Dog,Cow,Sheep,Pig

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human CITED1/ABCC1

Isotype: IgG

Information d'application

Indications d'application: FCM: (1:20-100)
Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Détail du antigène

Antigène: Cited1/Abcc1

Sujet:

Synonyms: ASD8, MRG1, VSD2, MRG-1, P35SRJ, Cbp/p300-interacting transactivator 2, MSG-related protein 1, CITED2

Background: Transcriptional coactivator of the p300/CBP-mediated trancription complex. Acts as a bridge, linking TFAP2 transcription factors and the p300/CBP transcriptional coactivator complex in order to stimulate TFAP2-mediated transcriptional activation. Positively regulates TGF-beta signaling through its association with the SMAD/p300/CBP-mediated transcriptional coactivator complex. Stimulates the peroxisome proliferator-activated receptors PPARA transcriptional activity. Enhances estrogen-dependent transactivation mediated by estrogen receptors. Acts also as a transcriptional corepressor, interferes with the binding of the transcription factors HIF1A or STAT2 and the p300/CBP transcriptional coactivator complex. Participates in sex determination and early gonad development by stimulating transcription activation of SRY. Plays a role in controlling left-right patterning during embryogenesis, potentiates transcriptional activation of NODAL-mediated gene transcription in the left lateral plate mesoderm (LPM). Plays an essential role in differentiation of the adrenal cortex from the adrenogonadal primordium (AGP), stimulates WT1-mediated transcription activation thereby up-regulating the nuclear hormone receptor NR5A1 promoter activity. Associates with chromatin to the PITX2 P1 promoter region.

ID gène: 10370

UniProt: Q99967