Claudin 22 (CLDN22) (AA 101-180) anticorps (FITC)

N° du produit ABIN2173205

L’anticorps Lapin Polyclonal anti- a été validé pour IF (cc) et IF (p). Il convient pour détecter dans des échantillons de Humain.

Aperçu rapide pour Claudin 22 (CLDN22) (AA 101-180) anticorps (FITC) (ABIN2173205)

Antigène: Claudin 22 (CLDN22)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: FITC

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit

Épitope: AA 101-180

Homologie: Human

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Claudin 22

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: Claudin 22 (CLDN22)

Autre désignation: Claudin 22

Sujet:

Synonyms: Claudin-22, CLD22_HUMAN, CLDN21,CLDN22, FLJ51450.

Background: The claudin superfamily consists of many structurally related proteins that are important structural and functional components of tight junctions in paracellular transport. Claudins are located in both epithelial and endothelial cells in all tight junction-bearing tissues. Claudins, which consist of four transmembrane domains and two extracellular loops, make up tight junction strands. It is suggested that the claudin family of proteins regulate transport through tight junctions via differential discrimination for solute size and charge. Claudin expression is often highly restricted to specific regions of different tissues and may have an important role in transcellular transport through tight junctions. Claudin-22, also known as CLDN22, is a 220 amino acid member of the claudin family that participates in tight junction-specific obliteration of the intercellular space through calcium-independent cell-adhesion activity.

Pathways: Cell-Cell Junction Organization, Hepatitis C