Rubella Virus Glycoprotein E1 (AA 801-900) anticorps (Cy7)

N° du produit ABIN2173792

Cet anticorps Lapin Polyclonal détecte spécifiquement Rubella Virus Glycoprotein E1 dans IF (cc) et IF (p). Il présente une réactivité avec des échantillons de Rubella Virus (RuV) et Virus.

Aperçu rapide pour Rubella Virus Glycoprotein E1 (AA 801-900) anticorps (Cy7) (ABIN2173792)

Antigène: Rubella Virus Glycoprotein E1

Reactivité: Rubella Virus (RuV), Virus

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cy7

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit

Épitope: AA 801-900

Réactivité croisée: Virus

Réactivité croisée (Details): Rubella virus

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from Rubella Virus E1 envelope glycoprotein

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: Rubella Virus Glycoprotein E1

Autre désignation: E1 glycoprotein

Classe de substances: Viral Protein

Sujet:

Synonyms: E1, E1 envelope glycoprotein, Glycoprotein E1, Spike glycoprotein E1, POLS_RUBVM.

Background: Rubella virus (RV), the sole member of the genus Rubivirus within the family Togaviridae, is a small enveloped, positive strand RNA virus. The nucleocapsid consists of 40S genomic RNA and a single species of capsid protein which is enveloped within a host-derived lipid bilayer containing two viral glycoproteins, E1 (58 kDa) and E2 (42-46 kDa). In virus infected cells, RV matures by budding either at the plasma membrane, or at the internal membranes depending on the cell type and enters adjacent uninfected cells by a membrane fusion process in the endosome, directed by E1-E2 heterodimers. The heterodimer formation is crucial for E1 transport out of the endoplasmic reticulum to the Golgi and plasma membrane. In RV E1, a cysteine at position 82 is crucial for the E1-E2 heterodimer formation and cell surface expression of the two proteins. E1 has been shown to be a type 1 membrane protein, rich in cysteine residues with extensive intramolecular disulphide bonds [PMID: 11682134]