Rubella Virus Glycoprotein E1 (AA 801-900) anticorps (FITC)

N° du produit ABIN2173793

L’anticorps anti-Rubella Virus Glycoprotein E1 Polyclonal Lapin est utilisé pour la détection de Rubella Virus Glycoprotein E1 dans des échantillons de Rubella Virus (RuV) et Virus. Il a été validé pour IF (cc) et IF (p).

Aperçu rapide pour Rubella Virus Glycoprotein E1 (AA 801-900) anticorps (FITC) (ABIN2173793)

Antigène: Rubella Virus Glycoprotein E1

Reactivité: Rubella Virus (RuV), Virus

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: FITC

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit

Épitope: AA 801-900

Réactivité croisée: Virus

Réactivité croisée (Details): Rubella virus

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from Rubella Virus E1 envelope glycoprotein

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: Rubella Virus Glycoprotein E1

Autre désignation: E1 glycoprotein

Classe de substances: Viral Protein

Sujet:

Synonyms: E1, E1 envelope glycoprotein, Glycoprotein E1, Spike glycoprotein E1, POLS_RUBVM.

Background: Rubella virus (RV), the sole member of the genus Rubivirus within the family Togaviridae, is a small enveloped, positive strand RNA virus. The nucleocapsid consists of 40S genomic RNA and a single species of capsid protein which is enveloped within a host-derived lipid bilayer containing two viral glycoproteins, E1 (58 kDa) and E2 (42-46 kDa). In virus infected cells, RV matures by budding either at the plasma membrane, or at the internal membranes depending on the cell type and enters adjacent uninfected cells by a membrane fusion process in the endosome, directed by E1-E2 heterodimers. The heterodimer formation is crucial for E1 transport out of the endoplasmic reticulum to the Golgi and plasma membrane. In RV E1, a cysteine at position 82 is crucial for the E1-E2 heterodimer formation and cell surface expression of the two proteins. E1 has been shown to be a type 1 membrane protein, rich in cysteine residues with extensive intramolecular disulphide bonds [PMID: 11682134]