Human Papilloma Virus E7 (HPV E7) (Middle Region) anticorps (Cy5.5)

N° du produit ABIN2173803

Cet anticorps anti-Human Papilloma Virus E7 Polyclonal Lapin conjugué à Cy5.5 (ABIN2173803) détecte spécifiquement Human Papilloma Virus E7 dans WB, FACS, IF (cc) et IF (p). L’anticorps est réactif avec des échantillons de Human Papillomavirus 16 (HPV-16).

Aperçu rapide pour Human Papilloma Virus E7 (HPV E7) (Middle Region) anticorps (Cy5.5) (ABIN2173803)

Antigène: Human Papilloma Virus E7 (HPV E7)

Reactivité: Human Papillomavirus 16 (HPV-16)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cy5.5

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit

Épitope: Middle Region

Specificité: This antibody may also detect HPV35-E7

Réactivité croisée: Humain, Virus

Réactivité croisée (Details): HPV16

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from middle of HPV16-E7

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: Human Papilloma Virus E7 (HPV E7)

Classe de substances: Viral Protein

Sujet:

Synonyms: Protein E7, E7

Background: Plays a role in viral genome replication by driving entry of quiescent cells into the cell cycle. Stimulation of progression from G1 to S phase allows the virus to efficiently use the cellular DNA replicating machinery to achieve viral genome replication. E7 protein has both transforming and trans-activating activities. Induces the disassembly of the E2F1 transcription factor from RB1, with subsequent transcriptional activation of E2F1-regulated S-phase genes. Interferes with host histone deacetylation mediated by HDAC1 and HDAC2, leading to transcription activation. Plays also a role in the inhibition of both antiviral and antiproliferative functions of host inteferon alpha.

ID gène: 1489079

UniProt: P03129