HPV16 E7 anticorps (Middle Region) (Cy7)

N° du produit ABIN2173804

Cet anticorps Lapin Polyclonal détecte spécifiquement HPV16 E7 dans WB, IF (p), FACS et IF (cc). Il présente une réactivité envers Human Papillomavirus 16 (HPV-16).

Aperçu rapide pour HPV16 E7 anticorps (Middle Region) (Cy7) (ABIN2173804)

Antigène: HPV16 E7 (HPV-16 E7) (Human Papilloma Virus 16 E7 (HPV-16 E7))

Reactivité: Human Papillomavirus 16 (HPV-16)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HPV16 E7 est conjugé à/à la Cy7

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc))

Détail du produit anti-HPV16 E7 anticorps (Cy7)

Épitope: Middle Region

Specificité: This antibody may also detect HPV35-E7

Réactivité croisée: Humain, Virus

Réactivité croisée (Details): HPV16

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from middle of HPV16-E7

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur HPV16 E7

Antigène: HPV16 E7 (HPV-16 E7) (Human Papilloma Virus 16 E7 (HPV-16 E7))

Classe de substances: Viral Protein

Sujet:

Synonyms: Protein E7, E7

Background: Plays a role in viral genome replication by driving entry of quiescent cells into the cell cycle. Stimulation of progression from G1 to S phase allows the virus to efficiently use the cellular DNA replicating machinery to achieve viral genome replication. E7 protein has both transforming and trans-activating activities. Induces the disassembly of the E2F1 transcription factor from RB1, with subsequent transcriptional activation of E2F1-regulated S-phase genes. Interferes with host histone deacetylation mediated by HDAC1 and HDAC2, leading to transcription activation. Plays also a role in the inhibition of both antiviral and antiproliferative functions of host inteferon alpha.

ID gène: 1489079

UniProt: P03129