H3 Histone Family Member E Pseudogene (acLys10), (pSer11) anticorps (Cy7)

N° du produit ABIN2175107

L’anticorps anti-H3 Histone Family Member E Pseudogene Polyclonal Lapin est utilisé pour la détection de H3 Histone Family Member E Pseudogene dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB.

Aperçu rapide pour H3 Histone Family Member E Pseudogene (acLys10), (pSer11) anticorps (Cy7) (ABIN2175107)

Antigène: H3 Histone Family Member E Pseudogene

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cy7

Application: Western Blotting (WB)

Détail du produit

Épitope: acLys10, pSer11

Réactivité croisée: Humain

Homologie: Mouse,Rat,Cow,Pig,Rabbit,Drosophila

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Acetyl and Histone H3 (Ac-Lys10/p-Ser11)

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: H3 Histone Family Member E Pseudogene

Sujet:

Synonyms: H3 histone family member E pseudogene, H3F3, HIST3H3, Histone H3 3 pseudogene.

Background: Modulation of the chromatin structure plays an important role in the regulation of transcription in eukaryotes. The nucleosome, made up of four core histone proteins (H2A, H2B, H3 and H4), is the primary building block of chromatin. The N-terminal tail of core histones undergoes different posttranslational modifications including acetylation, phosphorylation and methylation. These modifications occur in response to cell signal stimuli and have a direct effect on gene expression. In most species, the histone H2B is primarily acetylated at lysines 5, 12, 15 and 20. Histone H3 is primarily acetylated at lysines 9, 14, 18 and 23. Acetylation at lysine 9 appears to have a dominant role in histone deposition and chromatin assembly in some organisms. Phosphorylation at Ser10 of histone H3 is tightly correlated with chromosome condensation during both mitosis and meiosis.