HCFC1 anticorps (AA 201-300)

N° du produit ABIN2175231

Cet anticorps anti-HCFC1 est un anticorps Lapin Polyclonal détectant HCFC1 dans ELISA, IHC (p), IF (cc), IF (p) et IHC (fro). Adapté pour Souris.

Aperçu rapide pour HCFC1 anticorps (AA 201-300) (ABIN2175231)

Antigène: HCFC1 (Host Cell Factor C1 (VP16-Accessory Protein) (HCFC1))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HCFC1 est non-conjugé

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-HCFC1 anticorps

Épitope: AA 201-300

Réactivité croisée: Souris

Homologie: Human,Rat,Dog,Cow,Pig,Horse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human HCF-1

Isotype: IgG

Information d'application

Indications d'application: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur HCFC1

Antigène: HCFC1 (Host Cell Factor C1 (VP16-Accessory Protein) (HCFC1))

Autre désignation: HCF-1

Sujet:

Synonyms: C1 factor, CFF, HCF 1, HCF, HCF C-terminal chain 6, HCF-1, HCF1, Hcfc1, HCFC1_HUMAN, HFC1, Host Cell Factor-1, Host cell factor 1, Host cell factor, Host cell factor C1 (VP16 accessory protein), Host cell factor C1, MGC70925, VCAF, VP16 accessory protein, C1 factor, CFF, VCAF, VP16 accessory protein, HCF N-terminal chain 1, HCF N-terminal chain 2, HCF N-terminal chain 3, HCF N-terminal chain 4, HCF N-terminal chain 5, HCF N-terminal chain 6.

Background: Involved in control of the cell cycle. Also antagonizestransactivation by ZBTB17 and GABP2, represses ZBTB17 activation ofthe p15(INK4b) promoter and inhibits its ability to recruit p300.Coactivator for EGR2 and GABP2. Tethers the chromatin modifyingSet1/Ash2 histone H3 'Lys-4' methyltransferase (H3K4me) and Sin3histone deacetylase (HDAC) complexes (involved in the activationand repression of transcription, respectively) together. Componentof a THAP1/THAP3-HCFC1-OGT complex that is required for theregulation of the transcriptional activity of RRM1. As part of theNSL complex it may be involved in acetylation of nucleosomalhistone H4 on several lysine residues. In case of human herpessimplex virus (HSV) infection, HCFC1 forms a multiprotein-DNAcomplex with the viral transactivator protein VP16 and POU2F1thereby enabling the transcription of the viral immediate earlygenes.

ID gène: 3054