LAP3 anticorps (PE)
Aperçu rapide pour LAP3 anticorps (PE) (ABIN2177259)
Antigène
Voir toutes LAP3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Purification
- Purified by Protein A.
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Immunogène
- KLH conjugated synthetic peptide derived from human LAP3
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Isotype
- IgG
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Indications d'application
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FCM: (1:20-100)
Optimal working dilution should be determined by the investigator. -
Commentaires
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Exitation/Emission: 480,565nm/578nm
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at 4 °C for 12 months.
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- LAP3 (Cytosol Aminopeptidase (LAP3))
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Autre désignation
- Lap3
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Sujet
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LAP3 (leucine aminopeptidase 3), also known as LAPEP or PEPS, is a 519 amino acid protein that localizes to the cytoplasm and belongs to the peptidase M17 family. Existing as a homohexamer, LAP3 uses zinc as a cofactor to catalyze the release of an N-terminal proline from a target peptide and is, therefore, involved in the processing and turnover of intracellular proteins. Multiple isoforms of LAP3 exist due to alternative splicing events. The gene encoding LAP3 maps to human chromosome 4, which houses nearly 6 % of the human genome and has the largest gene deserts (regions of the genome with no protein encoding genes) of all of the human chromosomes. Defects in some of the genes located on chromosome 4 are associated with Huntington's disease, Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease.
Synonyms: Cytosol aminopeptidase, LAP 3, LAP, LAPEP, Leucine aminopeptidase 3, Leucyl aminopeptidase, PEPS, Peptidase S, Proline aminopeptidase, Prolyl aminopeptidase, AMPL_HUMAN. -
ID gène
- 51056
Antigène
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