DC-SIGN/CD209 anticorps

N° du produit ABIN217726

Cet anticorps Souris Monoclonal détecte spécifiquement DC-SIGN/CD209 dans FACS, IF et Func. Il présente une réactivité envers Humain.

Aperçu rapide pour DC-SIGN/CD209 anticorps (ABIN217726)

Antigène: DC-SIGN/CD209 (CD209) (CD209)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp DC-SIGN/CD209 est non-conjugé

Application: Flow Cytometry (FACS), Immunofluorescence (IF), Functional Studies (Func)

Clone: MR-1

Détail du produit anti-DC-SIGN/CD209 anticorps

Specificité: Recognizes human DC-specific ICAM-3 grabbing nonintegrin (DC-SIGN), a 45kD C-type lectin that binds ICAM-3 that is also known as CD209. CD209 is primarily expressed on a population of immature dendritic cells in peripheral tissues and on immature myeloid monocyte-derived DCs in vitro. CD209 is involved in dendritic cell (DC) migration and the initial interaction between DCs and naive T lymphocytes. CD209 also binds HIV-1 gp120 and plays a key role in the dissemination of HIV-1 by DCs. Clone MR-1 is reported to partially block the functional activity of DC-SIGN(2).

Purification: Protein G purified

niveau d'endotoxine: Low Endotoxin

Immunogène: Immature myeloid monocyte-derived dendritic cells (MDDCs).

Isotype: IgG1

Information d'application

Indications d'application: Approved: Flo, Func, IF

Usage: The applications listed have been tested for the unmodified form of this product. Other forms have not been tested. Flow Cytometry: Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL. Method sheets are available on request.

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.4.

Détails sur DC-SIGN/CD209

Antigène: DC-SIGN/CD209 (CD209) (CD209)

Autre désignation: CD209 / DC-SIGN

Sujet: Name/Gene ID: CD209

Synonyms: CD209, CD209 antigen, CD209 Molecule, CDSIGN, CLEC4L, DC-SIGN, HIV gpl20-binding protein, DC-SIGN1

ID gène: 30835