LCMV Protein Z (AA 21-80) anticorps

N° du produit ABIN2177284

Cet anticorps Lapin Polyclonal détecte spécifiquement dans IF (cc), IF (p), ELISA, IHC (fro), IHC (p) et ICC. Il présente une réactivité envers Lymphotic Choriomeniningitis Virus (LCMV) et Virus.

Aperçu rapide pour LCMV Protein Z (AA 21-80) anticorps (ABIN2177284)

Antigène: LCMV Protein Z

Reactivité: Lymphotic Choriomeniningitis Virus (LCMV), Virus

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Détail du produit

Épitope: AA 21-80

Réactivité croisée: Virus

Réactivité croisée (Details): Armstrong Strain LCMV

Attributs du produit: Antibody is specific for: Armstrong Strain LCMV

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from LCMV Protein Z

Isotype: IgG

Information d'application

Indications d'application: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: LCMV Protein Z

Classe de substances: Viral Protein

Sujet:

Synonyms: Lymphocytic choriomeningitis virus.RING finger protein Z, Protein Z, Zinc-binding protein, Z_LYCVA.

Background: Plays a crucial role in virion assembly and budding. Expressed late in the virus life cycle, it acts as an inhibitor of viral transcription and RNA synthesis by interacting with the viral polymerase L (By similarity). Presumably recruits the NP encapsidated genome to cellular membranes at budding sites via direct interaction with NP. Plays critical roles in the final steps of viral release by interacting with host TSG101, a member of the vacuolar protein-sorting pathway and using other cellular host proteins involved in vesicle formation pathway. The budding of the virus progeny occurs after association of protein Z with the viral glycoprotein complex SSP-GP1-GP2 at the cell periphery, step that requires myristoylation of protein Z. Also selectively represses protein production by associating with host eIF4E

UniProt: P18541